Luca Denti

 

I’m a PhD student in Computer Science at the department of Computer Science at the University of Milano-Bicocca (DISCo) since November 2016. My main interests involve combinatorial problems on strings, data structures, and graph theory. More broadly, I am also interested in programming languages.

My research activity focuses on biological problems that stem from the analysis of Next-Generation Sequencing data. In more detail, I tackled the problems of detecting Alternative Splicing events and variant genotyping.

Tools:

• ASGAL
  
• MALVA

Publications:

• Beretta Stefano, Bonizzoni Paola, Denti Luca, Previtali Marco and Rizzi Raffaella. Mapping RNA-seq Data to a Transcript Graph via Approximate Pattern Matching to a Hypertext
  International Conference on Algorithms for Computational Biology. Springer (2017)
• Denti Luca, Rizzi Raffaella, Beretta Stefano, Della Vedova Gianluca, Previtali Marco and Bonizzoni Paola. ASGAL: Aligning RNA-Seq Data to a Splicing Graph to Detect Novel Alternative Splicing Events
  BMC Bioinformatics (2018)
• Denti Luca*, Previtali Marco*, Bernardini Giulia, Schönhuth Alexander, Bonizzoni Paola. MALVA: genotyping by Mapping-free ALlele detection of known VAriants
  iScience (2019) [under review]
• Beretta Stefano, Denti Luca, Previtali Marco. Graph Theory and Definitions
  Encyclopedia of Bioinformatics and Computational Biology, Academic Press (2019)
• Beretta Stefano, Denti Luca, Previtali Marco. Network Properties
  Encyclopedia of Bioinformatics and Computational Biology, Academic Press (2019)

Talks:

• MALVA: genotyping by Mapping-free ALlele detection of known VAriants.
  RECOMB-SEQ (2019). Washington DC, USA
• MALVA: genotyping by Mapping-free ALlele detection of known VAriants.
  NGS Milano Meeting (2019). Milano, Italy
• Mapping RNA-seq Data to a Transcript Graph via Approximate Pattern Matching to a Hypertext.
  AlCoB (2017). Aveiro, Portugal

Posters:

• MALVA: genotyping by Mapping-free ALlele detection of known VAriants (RECOMB 2019)
  
• ASGAL: Aligning RNA-Seq Data to a Splicing Graph to Detect Novel Alternative Splicing Events (Best Poster at RECOMB 2018)

Awards:

• Best Poster Award, 22st International Conference on Research in Computational Molecular Biology, RECOMB (2018)

Studies:

• November 2014 – October 2016: Master’s Degree in Informatics (summa cum laude) from the University of Milano-Bicocca. Master’s Thesis: “A new algorithmic approach for the alignment of a string to a graph” Advisor: Prof.sa P. Bonizzoni Co-Advisors: Dott.sa R. Rizzi
• October 2011 – October 2014: Bachelor’s Degree in Informatics from the University of Milano-Bicocca. Bachelor’s Thesis: “Sviluppo di un simulatore di reti di Petri con raccolta di dati quantitativi” Advisor: Dott. L. Bernardinello Co-Advisor: Prof.sa L. Pomello

Contacts:

Email: l [dot] denti [atsymbol] campus [dot] unimib [dot] it

Address: Stanza 1001, c/o Edificio U14, Dip. di Informatica Sistemistica e Comunicazione, Viale Sarca, 336, I-20126 Milano (Italy)

Phone Number: +39 02 6448 7917